5-[2-(DIETHYLAMINO)ETHYL]-3-PHENYL-1,2,4-OXADIAZOLE CITRATE SALT Cas:1949-20-8

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5-[2-(DIETHYLAMINO)ETHYL]-3-PHENYL-1,2,4-OXADIAZOLE CITRATE SALT

Synonyms:
5-[2-(DIETHYLAMINO)ETHYL]-3-PHENYL-1,2,4-OXADIAZOLE CITRATE2,4-oxadiazole,5-(2-(diethylamino)ethyl)-3-phenyl-citrateCITRATO OXOLAMINAoxolamine dihydrogen citrateOxolaminCitrateOXOLAMINE CITRATEOXOLAMINE CITRATE SALT
 
molecular formula: C20H27N3O8
Molecular weight: 437.44400
 
Physical Properties:
Appearance and properties: white or off-white crystalline powder
Density: 1.066g/cm3
Boiling point: 364.8ºC at 760 mmHg
Melting point: 153-154ºC
Flash point: 174.4ºC

 
Specification:
Items of Analysis Standard of Analysis Test Results
Appearance White or almost white powder Conform
Solubility Slightly Soluble in Water and Methanol Conform
Identification IR Conform
Citric acid Content
(on dried basis)
42%-45% 43.8%
Melting Point 140℃-146℃ 142℃
pH 3.5-4.5 3.92
Loss on Drying ≤0.5% 0.11%
Residue on Ignition ≤0.2% 0.05%
Heavy Metals ≤0.002% Conform
Related Substances Benzamidoxime ≤0.1% Not detected
Max Single impurity ≤0.1% 0.06%
Total impurities ≤0.5% 0.11%
Residual Solvents Methanol ≤3000ppm Not detected
n-Hexane ≤290ppm Not detected
Chloroform ≤60ppm 7ppm
Particle Size 90% of particles : less than 15 μm 7.69μm
100% of particles: less than 45 μm 18.12μm
Assay 98%~102% 99.9%
Conclusion Conform to the enterprise standard
 
Application:
Oxolamine Citrate, is a antiinflammatory drug used as a cough suppressant.
 
Package and Storage:
Storage conditions: 2-8ºC
 
 



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