4,6-Dichloro-5-nitro-2-propylthiopyrimidine Cas:145783-14-8

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Product Description:

Product Name: 4,6-Dichloro-5-nitro-2-propylthiopyrimidine CAS NO:145783-14-8

Synonyms:

4,6-Dichloro-5-nitro-2-(propylthio)pyrimidine;

Chemical & Physical Properties:

Appearance : Yellow power

Assay :≥99.0%

Density:1.547g/cm3

Boiling Point:377.8℃ at 760 mmHg

Flash Point:182.3℃

Intermediate of Ticagrelor.

Ticagrelor is a new type of antiplatelet agglutinant, which was successfully developed by AstraZeneca in the United States. It is the world”s first reversible combined oral P2Y12 adenosine diphosphate receptor antagonist, which is reversible It acts on the purinoceptor2 (P2) subtype P2Y12 on vascular smooth muscle cells (VSMC), does not require metabolic activation, has a significant inhibitory effect on platelet aggregation caused by adenosine diphosphate (ADP), and is used orally The effect is rapid afterwards and can effectively improve the symptoms of patients with acute coronary heart disease.

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