4-methylquinoline Cas:491-35-0

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4-methylquinoline

Synonyms:
4-methyl quinoline
4-Methylquinoline
Lepidin
Quinoline,4-methyl
4-Methylquinoline,Lepidine
Cincholepidine
4-Lepidine
Quinoline, 4-methyl-
Lepidine
p-Methylquinoline

 
molecular formula: C10H9N
Molecular weight: 143.18500
 
Physical Properties:
Appearance and properties: colorless or yellow liquid
Density: 1.083 g/mL at 25 °C(lit.)
Boiling point: 261-263 °C(lit.)
Melting point: 9-10 °C (lit.)
Flash Point: >230 °F
Refractive index: n20/D 1.620(lit.)

 
Specification:
Items of Analysis Standard of Analysis Test Results
Appearance Colorless or straw yellow clarity oily liquid Conform
Assay ≥98.0% 98.25%
Moisture ≤0.5% 0.10%
Conclusion Conforms to Factory Standard
 

 
Application:
Used as an intermediate for dyes, pharmaceuticals, and photosensitive materials
 
Package and Storage:
25kgs/drum 
 
 



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TIGIT is highly expressed in gastric cancer. And pre-clinical experiments have proved that synergistically targeting PD-1 and TIGIT could significantly repress gastric tumor growth. We look forward to the clinical results of IBI321, particularly in GI tumors.
Dr. Hui Zhou, Senior Vice President of Clinical Development of Innovent, stated: “By specifically targeting both PD-1 and TIGIT, this type of bispecific antibody is designed to provide synergistic effects by blocking both the PD-1/PD-L1 and TIGIT/CD155 pathways – with the goal of improving the anti-cancer efficacy.
Currently, there is no bispecific antibody that has same target as IBI321 in clinical-stage development worldwide. Preclinical studies of IBI321 have demonstrated that the combination of these two monoclonal antibodies further enhanced the immune activation with improved convenience of administration.
Therefore, the development of an anti-PD-1/TIGIT bispecific antibody has the potential to provide patients with more effective and convenient treatment. We look forward to hope that IBI321 will benefit more patients. (4aS,6R,8aS)-3-methoxy-11-(methyl-14C)-4a,5,9,10,11,12-hexahydro-6H-benzo[2,3]benzofuro[4,3-cd]azepin-6-ol supplier.In his new role, Grégoire will ensure alignment between NOVA’s business strategy, operations and growth objectives, as well as leading the Modelling and Simulation (M&S) team as NOVA embarks on its next phase of expansion. Urea, N-(3-chloro-1,2-benzisothiazol-5-yl)-N’-phenyl- producer.

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