(2b,3a,5a,16b,17b)-2-(4-Morpholinyl)-16-(1-pyrrolidinyl)androstane-3,17-diol Cas:119302-20-4

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2,3-Epoxy-1H-cyclopenta[a]phenanthrene,anddrostan-17-ol deriv
RocuroniuM BroMide InterMediate VII

Molecular Formula: C27H46N2O3
Molecular weight: 446.66600
Physical Properties:
Appearance and properties: whitish or light yellow crystalline powder
Density: 1.163
Boiling point: 565.4ºC at 760 mmHg
Melting point: 161-169ºC
Flash point: 295.7ºC
Refractive index: 1.574

Items of Analysis Standard of Analysis Test Results
Appearance White to off-white crystalline powder Conform
Solubility Very slightly soluble in methanol and Acetonitrile Conform
Loss on drying Not more than 1% 0.41%
Residue on ignition Not more than 0.2% 0.09%
Specific optical rotation (calculated on dried basis) +80° to +90° +86°
Largest single impurity Not more than 0.25% Conform
Total impurities Not more than 1.0% Conform
Purity ( calculated on dried basis) Not less than 99% Conform
Conclusion Conforms to Factory Standard

It is an intermediate in the production of anesthesia adjuvant drug rocuronium bromide.
Package and Storage:

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