2′,3′,5′-Triacetyl -azacytidine

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Chemical Name:2',3',5'-Triacetyl -azacytidine
CAS.NO:10302-78-0
Synonyms:4-amino-1-(2,3,5-tri-O-acetylpentofuranosyl)-1,3,5-triazin-2(1H)-one
2',3',5'-triacetyl-5-Azacytosine
1,3,5-Triazin-2(1H)-one,4-amino-1-(2,3,5-tri-O-acetyl-b-D-ribofuranosyl)
2,3,5-tri-O-acetyl-5-azacytidine
5-azacytidine triacetate
Molecular Formula:C14H18N4O8
Molecular Weight:370.31500
 
Physical and Chemical Properties:
Density:1.6
Boiling point:497.3ºC
Flash point:254.6ºC
Index of Refraction:1.633
 
Specification:
Appearance:White to off-white crystalline powder
Assay(HPLC):≥98.0%
 
Packing:25 kg/drum, can also be packaged according to customer requirements
Storage:Store in a cool, ventilated place
Application:5-Azacytidine 2’,3’5’-O-triacetate is a useful compound for the treatment and prevention of cancer and disorders related to abnormal cell proliferation, hematological disorders, and myelodysplastic syndromes (MDS). It can be also used to synthesize 2'3'5'triacetyl-5-azacytidine which is a prodrug for azacitidine. Azacitidine is a FDA-appproved DNA metnyltransferase (DNMT) inhibitor.

2',3',5'-Triacetyl -azacytidine


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