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Product Description:
Product Name: 1,2,3-1H-Triazole CAS NO: 288-36-8
Synonyms:
1-H-triazole;
vic-triazole;
1H-[1,2,3]triazole;
Chemical & Physical Properties:
Appearance: Colorless liquid
Assay :≥99.00%
Density: 1.192
Boiling Point: 203℃ (752 mmHg)
Melting Point: 23-25℃
Flash Point: 107℃
Refractive Index: 1.493-1.496
Water Solubility: Soluble
Storage Condition: Store in a cool, dry place. Store in a tightly closed container.
Safety Information:
Safety Statements: S26-S37/39
HS Code: 2933990090
WGK Germany: 3
Risk Statements: R36/37/38
Hazard Codes: Xi,Xn
1,2,3-Triazole is one of a pair of isomeric chemical compounds with molecular formula C2H3N3, called triazoles, which have a five-membered ring of two carbon atoms and three nitrogen atoms. 1,2,3-Triazole is a basic aromatic heterocycle.
Substituted 1,2,3-triazoles can be produced using the azide alkyne Huisgen cycloaddition in which an azide and an alkyne undergo a 1,3-dipolar cycloaddition reaction.
It is a surprisingly stable structure compared to other organic compounds with three adjacent nitrogen atoms. However, flash vacuum pyrolysis at 500 °C leads to loss of molecular nitrogen (N2) to produce aziridine. Certain triazoles are relatively easy to cleave due to so-called ring-chain tautomerism. One manifestation is found in the Dimroth rearrangement.
1,2,3-Triazole finds use in research as a building block for more complex chemical compounds, including pharmaceutical drugs such as tazobactam.
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