1,2,3-1H-Triazole Cas:288-36-8

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Product Description:

Product Name: 1,2,3-1H-Triazole CAS NO: 288-36-8

 

Synonyms:

1-H-triazole;

vic-triazole;

1H-[1,2,3]triazole;

 

Chemical & Physical Properties:

Appearance: Colorless liquid

Assay :≥99.00%

Density: 1.192

Boiling Point: 203℃ (752 mmHg)

Melting Point: 23-25℃

Flash Point: 107℃

Refractive Index: 1.493-1.496

Water Solubility: Soluble

Storage Condition: Store in a cool, dry place. Store in a tightly closed container.

 

Safety Information:

Safety Statements: S26-S37/39

HS Code: 2933990090

WGK Germany: 3

Risk Statements: R36/37/38

Hazard Codes: Xi,Xn

 

1,2,3-Triazole is one of a pair of isomeric chemical compounds with molecular formula C2H3N3, called triazoles, which have a five-membered ring of two carbon atoms and three nitrogen atoms. 1,2,3-Triazole is a basic aromatic heterocycle.

Substituted 1,2,3-triazoles can be produced using the azide alkyne Huisgen cycloaddition in which an azide and an alkyne undergo a 1,3-dipolar cycloaddition reaction.

It is a surprisingly stable structure compared to other organic compounds with three adjacent nitrogen atoms. However, flash vacuum pyrolysis at 500 °C leads to loss of molecular nitrogen (N2) to produce aziridine. Certain triazoles are relatively easy to cleave due to so-called ring-chain tautomerism. One manifestation is found in the Dimroth rearrangement.

1,2,3-Triazole finds use in research as a building block for more complex chemical compounds, including pharmaceutical drugs such as tazobactam.

 

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