1-ethenylpyrrolidin-2-one Cas:25249-54-1

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1-ethenylpyrrolidin-2-one

Synonyms:
1-ethenylpyrrolidin-2-one
Pvpp
Polyvidone
N-Vinylpyrrolidone
Poly(vinylpolypyrrolidone)
2-Pyrrolidinone,1-ethenyl
Polyvinylpyrrolidone
1-Vinyl-2-pyrrolidinone
crospovidone
Povidone
Vinylpyrrolidone
polyvinylpolypyrrolidone
Polyvinylpyrrolidone (PVP-P)
1-Vinyl-2-pyrrolidone

 
molecular formula: C18H27N3O3
Molecular weight: 333.42500
 
Physical Properties:
Appearance: powder | White to off-white
Density: 1.1±0.1 g/cm3
Boiling point: 217.6±7.0 °C at 760 mmHg
Melting point: ~165 °C (dec.)(lit.)
Vapor Pressure: 0.1±0.4 mmHg at 25°C
Refractive index: 1.593

 
Specification:
Test Specification Results
Appearance White or yellowish-white hygroscopic powder Complies
Identification, ABC Positive Complies
Appearance of solution Solution S is clear
coloration = B6,BY6,or R6
Complies
PH (in 5% solution ) 3.0-7.0 5.8
Viscosity, as K-value 81.0-97.2 92.6
Lead =10ppm Complies
Impurity A,(1-Vinylpyrrolidin-2-one) W0.1% 0.04%
Water W5.0% 2.5%
Sulphated ash M0.1% 0.05%
Assay, as Nitrogen content 11.5-12.8% 12.2%
Microbiological status Max. 100 aerobic plate count CFU/g
 
<10
Max. 100 Mold and Yeast CFU/g <10
 No Escherichia Coli /g
 
Complies
No Pseudomonas aeruginosa /g Complies
No Salmonella /10g Complies
No staphylococcus aureus /g Complies
 
Application:
Polyvinylpolypyrrolidone (polyvinyl polypyrrolidone, PVPP, crospovidone, crospolividone or E1202) is a highly cross-linked modification of polyvinylpyrrolidone (PVP).
The cross-linked form of PVP is used as a disintegrant (see also excipients) in pharmaceutical tablets. PVPP is a highly cross-linked version of PVP, making it insoluble in water, though it still absorbs water and swells very rapidly generating a swelling force. This property makes it useful as a disintegrant in tablets.
PVPP can be used as a drug, taken as a tablet or suspension to absorb compounds (so-called endotoxins) that cause diarrhoea. (Cf. bone char, charcoal.); It is also used as a fining to extract impurities (via agglomeration followed by filtration). It is used in winemaking. Using the same principle it is used to remove polyphenols in beer production and thus clear beers with stable foam are produced. One such commercial product is called Polyclar. PVPP forms bonds similar to peptidic bonds in protein (especially, like proline residues) and that is why it can precipitate tannins the same way as proteins do.
PVPP has E number code E1202 and is used as a stabiliser
 
Package and Storage:
1kg/bottle or bag
25kgs/drum or bag
 
 



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