1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide Cas:1892-57-5

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Product Description:

Product Name: 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide CAS NO:1892-57-5

 

Synonyms:

3-(ethyliminomethylideneamino)-N,N-dimethylpropan-1-amine;

1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide;

 

Chemical & Physical Properties:

Appearance: Colorless to slightly yellow liquid

Assay :≥98.0%

Density: 0.877g/cm3

Boiling point:197.7℃ at 760 mmHg

Flash Point:73.4℃

Melting point:115℃

 

1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC, EDAC or EDCI) is a water-soluble carbodiimide usually obtained as the hydrochloride. It is typically employed in the 4.0-6.0 pH range. It is generally used as a carboxyl activating agent for the coupling of primary amines to yield amide bonds. Additionally, EDC can also be used to activate phosphate groups in order to form phosphomono-esters and phosphodiesters. Common uses for this carbodiimide include peptide synthesis, protein crosslinking to nucleic acids, but also in the preparation of immunoconjugates. EDC is often used in combination with N-hydroxysuccinimide (NHS) for the immobilisation of large biomolecules.

 

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