Β-Nicotinamide Adenine Dinucleotide NAD Cas:53-84-9

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Product Description:

Product Name: β-Nicotinamide Adenine Dinucleotide NAD CAS NO 53-84-9

 

Synonyms:

beta-Diphosphopyridine nucleotide;

Coenzyme I Hydrate,oxidized form;

beta-NAD+; 

Pyridinium, 3-carbamoyl-1-beta-D-ribofuranosyl-, hydroxide, 5”-ester with adenosine 5”-5”-(trihydrogen pyrophosphate), inner salt;

[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2R,3S,4R,5R)-5-(3-carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphate;

 

Chemical & Physical Properties:

Appearance : White to Yellowish powder.

Assay : ≥99.0%

Melting point: 140-142℃

PSA: 340.71000

LogP: -1.29620

Solubility: Soluble in water, insoluble in acetone and other organic solvents.

Stability:  Stable. Hygroscopic. Incompatible with strong oxidizing agents.

Water Solubility: 50 mg/mL.

 

The product is easy to absorb moisture and the aqueous solution is acid. The solid is stable under dry conditions. The product can be stored in neutral or weak acid aqueous solution room temperature for 7 days, and will accelerate deterioration and decomposition in case of alkali and heat.

Specific rotation [α] 23d-34.8 ° (1%, water); the maximum absorption of aqueous solution is at 260nm and 340nm.

Category: Enzymes and Coenzymes in Nucleic Acids; Nucleosides, Nucleotides & Related Reagents;Vitamin Related Compounds; Pharmaceutical/API Drug Intermediates;

 

Safety Information

HS Code: 2934999099

Safety Statements: S24/25

Risk Statements:R36

Hazard Codes: Xn; F; Xi

 

Storage：Stored in a cool and dry well-closed container. Keep away from moisture and strong light/heat.

 

Application:

1. β-NAD is an essential coenzyme for biochemical research, clinical diagnosis, clinical drugs and drug research.

2. β-Nicotinamide adenine dinucleotide hydrate is mainly used in clinical adjuvant treatment of coronary heart disease, can improve chest distress angina pectoris and other symptoms of adverse reactions occasionally dry mouth dizziness and nausea.

3. NAD is involved in energy metabolism and material metabolism in vivo, which is conducive to cell repair and renewal for the treatment of coronary heart disease, myocarditis, leukopenia and other diseases.

4. B-Nicotinamide adenine dinucleotide acts as a coenzyme in redox reactions, as a donor of ADP-ribose moieties in ADP-ribosylation reactions and also as a precursor of the second messenger molecule cyclic ADP-ribose. β-Nicotinamide Adenine Dinucleotide also acts as a substrate for bacterial DNA ligases and a group of enzymes called sirtuins that use NAD+ to remove acetyl groups from proteins.

 

Our factory manufacture’s β-DPN Hydrate,oxidized form, mature technology, stable output, quality assurance.

Inventory Status : In Stock.

 

We can provide beta-Diphosphopyridine nucleotide COA (certificate of analysis), beta-Diphosphopyridine MOA (Method of Analysis), β-NAD Hydrate,oxidized form ROS (Route of synthesis), Diphosphopyridine nucleotide MSDS (Material Safety Data Sheet) and other support for you !

 

β-Diphosphopyridine Nucleotide Hydrate,oxidized form (NAD+) plays a major role in metabolism as a cofactor and mobile electron acceptor. NAD+ is a required oxidizing cosubstrate for many enzymes. It is reduced to NADH which carries electrons to the electron transport chain for subsequent oxidative phorphorylation and ATP production. NAD+ is capable of donating ADP-ribose moieties to a protein, producing nicotinamide in the process. Sirtuin enzymes use NAD+ as a substrate to deacetylate proteins and direct activity between the nucleus and mitochondria. NAD+ is regenerated by fermentation and by oxidative phosphorylation.

 

If you are interested in our products or have any questions, please feel free to contact us!

 

Products under patent are offered for R & D purpose only. However, the final responsibility lies exclusively with the buyer.

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